Toufeeq Khan T F, Hayat F Z, Muniandy S
Department of Surgery, Hospital University Sains Malaysi, Kelantan, Malaysia.
Singapore Med J. 1998 Jan;39(1):25-6.
Anomalous pancreatico-biliary junction (APBJ) is commonly associated with cystic dilatation of the bile ducts but recently, several cases without the cystic dilatation have been reported. We treated a young female patient with intractable back and epigastric pain of three months duration. The spine was normal on magnetic resonance imaging (MRI), but several lymph nodes were seen around the coeliac axis. An APBJ, a non-cystic biliary system, non-filling of the gallbladder and an irregular right margin of the bile duct were evident on endoscopic retrograde pancreatography (ERCP), which was highly suggestive of gallbladder (GB) malignancy. At surgery, the GB was hard with local infiltration of the bile duct. Numerous large para-aortic and supraduodenal lymph nodes were present and only a biopsy was possible. Details of the case are presented and the growing etiological importance of an APBJ, especially without cystic biliary dilatation in gallbladder carcinogenesis is discussed.
胰胆管异常连接(APBJ)通常与胆管囊性扩张有关,但最近有报道称有几例无囊性扩张的病例。我们治疗了一名患有持续三个月顽固性背部和上腹部疼痛的年轻女性患者。磁共振成像(MRI)显示脊柱正常,但在腹腔干周围可见多个淋巴结。内镜逆行胰胆管造影(ERCP)显示有APBJ、非囊性胆管系统、胆囊未显影以及胆管右缘不规则,高度提示胆囊(GB)恶性肿瘤。手术中,胆囊质地坚硬,胆管有局部浸润。存在大量主动脉旁和十二指肠上淋巴结,仅能进行活检。本文介绍了该病例的详细情况,并讨论了APBJ在病因学上日益重要的作用,尤其是在胆囊癌变中无胆管囊性扩张的情况。