Shoenut J P, Duerksen D, Yaffe C S
St. Boniface General Hospital, and Department of Medicine, University of Manitoba, Winnipeg, Canada.
Dig Dis Sci. 1998 Apr;43(4):834-9. doi: 10.1023/a:1018882501843.
A prospective investigation of the impact of ingested liquids on 24-hr pH test scores was conducted. Eighty-two patients contributed 142 samples. The liquids used were coffee/tea (N = 35), water (N = 32), fruit juice (N = 29), cola (N = 34), and beer (N = 12). The pH of cola, juice, and beer are approximately 3.0. The parameters studied included: total test time, total drink time, total minutes of pH < 4.0 during drink, minutes of < pH 4.0 10 min before drink, and minutes of pH < 4.0 10 min following drink. Analysis was performed using one-way ANOVA and repeated measures. Age of patients, total test time, and total time pH < 4.0 were not significantly different (P > 0.05). The total time to consume the drink was significantly greater (P < 0.05) for beer than all other liquids. The total time (7.7 +/- 6.0 min) pH < 4.0 for cola was significantly different (P < 0.023) than beer (3.3 +/- 3.7 min), tea/coffee (1.4 +/- 6.5 min), and water (1.1 +/- 2.5 min). The percentage of total time pH < 4.0 was not significantly different (P > 0.05) among any of the liquids. The percentage of time pH < 4.0 during the drink was the highest for cola (63 +/- 47%) and juice (51 +/- 57%); water, coffee/tea, and beer were not significantly different (P > 0.05). Although the impact of cola and juice were the greatest, none of these had an impact that exceeded 0.5%. The lack of impact of beer appears to be due to the increased period of time it takes to consume. We conclude that the impact of ingested fluids is minimal and can probably be disregarded in most patient groups.
开展了一项关于摄入液体对24小时pH测试分数影响的前瞻性调查。82名患者提供了142份样本。所使用的液体为咖啡/茶（N = 35）、水（N = 32）、果汁（N = 29）、可乐（N = 34）和啤酒（N = 12）。可乐、果汁和啤酒的pH值约为3.0。所研究的参数包括：总测试时间、总饮用时间、饮用期间pH值<4.0的总分钟数、饮用前10分钟pH值<4.0的分钟数以及饮用后10分钟pH值<4.0的分钟数。采用单因素方差分析和重复测量进行分析。患者年龄、总测试时间以及pH值<4.0的总时间无显著差异（P>0.05）。饮用啤酒的总时间显著长于所有其他液体（P<0.05）。可乐pH值<4.0的总时间（7.7±6.0分钟）与啤酒（3.3±3.7分钟）、茶/咖啡（1.4±6.5分钟）和水（1.1±2.5分钟）相比有显著差异（P<0.023）。任何一种液体中pH值<4.0的总时间百分比无显著差异（P>0.05）。饮用期间pH值<4.0的时间百分比以可乐（63±47%）和果汁（51±57%）最高；水、咖啡/茶和啤酒无显著差异（P>0.05）。尽管可乐和果汁的影响最大，但这些影响均未超过0.5%。啤酒影响不明显似乎是由于饮用时间延长。我们得出结论，摄入液体的影响极小，在大多数患者群体中可能可以忽略不计。
