Arlette J P, Carruthers A, Threlfall W J, Warshawski L M
Division of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada.
J Cutan Med Surg. 1998 Apr;2(4):205-8. doi: 10.1177/120347549800200405.
Basal cell carcinomas of the periocular area present a particular challenge because of the likelihood of damage to vital structures.
More than 10-years experience of treating basal cell carcinomas by Mohs micrographic surgery was reviewed.
Chart analysis of 233 periocular basal cell carcinomas was performed. All patients were contacted either in clinical follow-up or by telephone review.
Two hundred and thirty-three periocular basal cell carcinomas were analyzed out of a total of 3, 192 basal cell carcinomas treated during this period (7.3%). Patients ranged in age from 17 to 102 years with a mean age of 58.8 years and a median of 59.0 years. Of the patients, 54.5% were female. Mohs micrographic surgery was the prime therapy in 177 patients (75. 9%). Of the lesions, 48.5% occurred in the medial canthal area, 35. 2% on the lower eyelid, 10.7% on the upper eyelid, and 5.6% on the lateral canthus. There was no significant difference between the left/right distribution in males and females. The average follow-up time was 34 months (standard deviation 26.38 months). A cumulative rate of no recurrence tabulated by modified life table analysis was 0.9864.
This study further documents the problems associated with basal cell carcinoma of the periocular area as well as the value of Mohs micrographic surgery as treatment.
眼周区域的基底细胞癌由于可能损害重要结构而带来特殊挑战。
回顾超过10年采用莫氏显微外科手术治疗基底细胞癌的经验。
对233例眼周基底细胞癌进行图表分析。所有患者均通过临床随访或电话回访进行联系。
在此期间治疗的3192例基底细胞癌中，分析了233例眼周基底细胞癌（7.3%）。患者年龄范围为17至102岁，平均年龄58.8岁，中位数为59.0岁。其中54.5%为女性。177例患者（75.9%）以莫氏显微外科手术作为主要治疗方法。在这些病变中，48.5%发生在内眦区域，35.2%在下眼睑，10.7%在上眼睑，5.6%在外眦。男性和女性的左右分布之间无显著差异。平均随访时间为34个月（标准差26.38个月）。通过修正寿命表分析列出的无复发累积率为0.9864。
本研究进一步记录了眼周区域基底细胞癌相关问题以及莫氏显微外科手术作为治疗方法的价值。
