Kalaaji A N, Douglass M C, Chaffins M, Lowe L
Department of Dermatology Henry Ford Hospital, Detroit, Michigan 48202, USA.
J Cutan Med Surg. 1998 Apr;2(4):242-4. doi: 10.1177/120347549800200414.
Calciphylaxis is a rare and life-threatening condition occurring in patients with end-stage renal disease on dialysis. The diagnosis is frequently delayed or missed and therapy is often unsuccessful.
The clinical and pathological components of calciphylaxis are emphasized in a patient that may facilitate early diagnosis and initiation of therapy.
Early recognition of the clinical signs and symptoms of calciphylaxis is crucial. The tissue diagnosis requires large elliptical biopsies because histological findings are segmental and often missed.
Early diagnosis and intervention in calciphylaxis is critical. Parathyroidectomy should be considered in all cases.
钙化防御是一种发生于终末期肾病透析患者的罕见且危及生命的病症。诊断常常延迟或漏诊，治疗往往不成功。
强调钙化防御的临床和病理特征，这可能有助于患者的早期诊断及治疗启动。
早期识别钙化防御的临床体征和症状至关重要。组织诊断需要取大的椭圆形活检标本，因为组织学表现是节段性的，常被漏诊。
钙化防御的早期诊断和干预至关重要。所有病例均应考虑行甲状旁腺切除术。
