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印度恒河豚肝脏中的尿素循环酶

Urea cycle enzymes in the liver of a dolphin Platanista indi.

作者信息

Grillo M A, Sisini A

出版信息

Ital J Biochem. 1976 May-Jun;25(3):219-28.

PMID:955855
Abstract

Urea cycle enzymes are all shown to be active in dolphin liver. Acetylglutamate-independent cytoplasmic carbamylphosphate synthase is also present. Arginase is a basic protein, although less markedly basic than the dog enzyme. It is 118 per cent activated by heating at 50 degrees. Optimum pH is 10.5. Co++ and Ni++ inhibit the enzyme. AMP deaminase, glutamicoxaloacetic transaminase, glutamate dehydrogenase and ornithine transaminase are also active in dolphin liver.

摘要

已证实尿素循环酶在海豚肝脏中均具有活性。也存在不依赖于乙酰谷氨酸的细胞质氨基甲酰磷酸合成酶。精氨酸酶是一种碱性蛋白,不过其碱性不如犬类的酶那么明显。在50摄氏度加热可使其活性提高118%。最适pH值为10.5。Co++和Ni++会抑制该酶。AMP脱氨酶、谷草转氨酶、谷氨酸脱氢酶和鸟氨酸转氨酶在海豚肝脏中也具有活性。

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