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大鼠体内Endo-Fill根管封闭剂和充填材料组织反应的组织病理学评估

Histopathological evaluation of the tissue reactions to Endo-Fill root canal sealant and filling material in rats.

作者信息

Görduysus M O, Etikan I, Gököz A

机构信息

Department of Endodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.

出版信息

J Endod. 1998 Mar;24(3):194-6. doi: 10.1016/S0099-2399(98)80182-9.

DOI:10.1016/S0099-2399(98)80182-9
PMID:9558586
Abstract

In this in vivo study, the tissue reactions to silicone-based Endo-Fill root canal filling material were histopathologically evaluated. The reaction of rat connective tissue to polyethylene tube implants that were filled with Endo-Fill were evaluated at 2 days, at 1, 2, 4, and 8 weeks. Four tube were implanted in each rat subcutaneously, and a total of 15 rats were used. Rats were killed, and the specimens were examined under the light microscope (x115 and x230). At the end of 8 wk, a thin fibrous wall with an almost completed advanced healing process was observed around the implant material, but no capsule formation or any inflammatory infiltration was seen.

摘要

在这项体内研究中,对硅基Endo-Fill根管充填材料的组织反应进行了组织病理学评估。在第2天、第1、2、4和8周时评估大鼠结缔组织对填充有Endo-Fill的聚乙烯管植入物的反应。每只大鼠皮下植入4根管,共使用15只大鼠。处死大鼠,将标本在光学显微镜下(×115和×230)检查。在8周结束时,在植入材料周围观察到一个几乎完成了高级愈合过程的薄纤维壁,但未观察到包膜形成或任何炎症浸润。

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