Angelova K C, Angelov C G
National Center of Hygiene, Ecology and Nutrition, Sofia, Bulgaria.
Z Ernahrungswiss. 1998;37 Suppl 1:98-102.
Circadian oscillations of liver tyrosine aminotransferase (TAT) tryptophan oxygenase (TO), alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT), and glutamate dehydrogenase (GLDH) in temporal pattern of protein input have been investigated. Cosinor analysis of oscillations parameters revealed the glucocorticoid induction of TO activity and protein induction of TAT activity rhythm. ALAT, ASAT, and GLDH activities showed 24 h fluctuations, but the regulation mechanisms remain unclear.
已对蛋白质输入时间模式下肝脏酪氨酸转氨酶(TAT)、色氨酸加氧酶(TO)、丙氨酸转氨酶(ALAT)、天冬氨酸转氨酶(ASAT)和谷氨酸脱氢酶(GLDH)的昼夜振荡进行了研究。振荡参数的余弦分析揭示了糖皮质激素对TO活性的诱导以及TAT活性节律的蛋白质诱导。ALAT、ASAT和GLDH活性呈现24小时波动,但调控机制仍不清楚。