Kálai T, Hideg E, Vass I, Hideg K
Institute of Organic and Medicinal Chemistry, University of Pécs, Hungary.
Free Radic Biol Med. 1998 Mar 1;24(4):649-52. doi: 10.1016/s0891-5849(97)00339-0.
A series of dansylated sterically hindered amines designed to trapping reactive oxygen species, were synthesized. Compounds were tested in isolated thylakoid membranes subjected to photoinhibition by excess photosynthetically active radiation (400-700 nm). DanePy showed good selectivity for singlet oxygen and the formation of nitroxide was detected by appearance of ESR signal and quenching fluorescence.
合成了一系列旨在捕获活性氧的丹磺酰化位阻胺。在受到过量光合有效辐射(400 - 700 nm)光抑制的分离类囊体膜中对化合物进行了测试。DanePy对单线态氧表现出良好的选择性,通过电子顺磁共振信号的出现和荧光猝灭检测到了氮氧化物的形成。