由锡安小单孢菌产生的新型氨基环醇-氨基糖苷类抗生素G-52的结构。

The structure of antibiotic G-52, a new aminocyclitol-aminoglycoside antibiotic produced by Micromonospora zionensis.

作者信息

Daniels P J, Jaret R S, Nagabhushan T L, Turner W N

出版信息

J Antibiot (Tokyo). 1976 May;29(5):488-91. doi: 10.7164/antibiotics.29.488.

DOI:10.7164/antibiotics.29.488

Abstract

Antibiotic G-52, a new aminocyclitol-aminoglycoside antibiotic produced in the fermentation of Micromonospora zionensis, has been shown to be 6'-N-methylsisomicin on the basis of its spectral characteristics. This assignment was confirmed by synthesis of the antibiotic from sisomicin.

摘要

抗生素G-52是由锡安小单孢菌发酵产生的一种新型氨基环醇-氨基糖苷类抗生素，根据其光谱特征显示它是6'-N-甲基西索米星。通过由西索米星合成该抗生素，这一归属得以证实。