抗生素333 - 25的组成氨基酸和脂肪酸。（芽孢杆菌属抗生素的研究。第十二部分）

The constituent amino acids and fatty acid of antibiotic 333-25. (Studies on antibiotics from the genus Bacillus. XII.

作者信息

Shoji J, Hinoo H, Sakazaki R

出版信息

J Antibiot (Tokyo). 1976 May;29(5):521-5. doi: 10.7164/antibiotics.29.521.

DOI:10.7164/antibiotics.29.521

Abstract

Measurement of the optical rotational activities of the constituent amino acids of antibiotic 333-25 identified 2,4-diaminobutyric acid (D-form 1, L-form 4), L-leucine (2) and D-phenylalanine (1). The fatty acid constituent was determined to be beta-hydroxy anteisononanoic acid by gas chromatography, nuclear magnetic resonance and mass spectra. Differentiation from the structure of antibiotic EM 49 is discussed.

摘要

对抗生素333 - 25的组成氨基酸的旋光活性进行测量，鉴定出2,4 - 二氨基丁酸（D型1个，L型4个）、L - 亮氨酸（2个）和D - 苯丙氨酸（1个）。通过气相色谱法、核磁共振和质谱法确定其脂肪酸成分为β - 羟基反异壬酸。文中还讨论了与抗生素EM 49结构的差异。