Aono M, Sata J, Nishino T
Department of Anesthesiology, Chiba University School of Medicine.
Masui. 1998 Mar;47(3):335-40.
In order to evaluate cerebral oxygenation and perfusion during deep hypothermic circulatory arrest (DHCA) and selective cerebral perfusion (SCP), continuous measurement of regional cerebral oxygen saturation (rSO2) by near-infrared spectroscopy (NIRS) was performed. Two patients undergoing aortic arch surgery performed under DHCA and SCP were studied. 1) Circulatory arrest produced a continuous decrease in rSO2. Introduction of SCP increased rSO2 to even above the pre-circulatory arrest level (reperfusion hyperoxia). 2) During SCP, changes in rSO2 correlated well with the naso-pharyngeal temperature, SCP flow rate, and level of carbon-dioxide insufflation to SCP. 3) These changes in rSO2 paralleled with those of jugular venous hemoglobin saturation (SjO2) measured simultaneously, although SjO2 frequently exhibited artifacts. We conclude that rSO2 measurement may be a non-invasive and continuous measure in the evaluation of cerebral oxygenation and perfusion during DHCA and SCP.
为了评估深低温停循环(DHCA)和选择性脑灌注(SCP)期间的脑氧合和灌注情况,采用近红外光谱法(NIRS)对局部脑氧饱和度(rSO2)进行了连续测量。对2例在DHCA和SCP下进行主动脉弓手术的患者进行了研究。1)停循环导致rSO2持续下降。引入SCP后,rSO2升高甚至超过停循环前水平(再灌注性高氧)。2)在SCP期间,rSO2的变化与鼻咽温度、SCP流速以及SCP的二氧化碳吹入水平密切相关。3)尽管颈静脉血红蛋白饱和度(SjO2)经常出现伪像,但rSO2的这些变化与同时测量的SjO2变化相似。我们得出结论,rSO2测量可能是评估DHCA和SCP期间脑氧合和灌注的一种非侵入性连续测量方法。