Povýsil C
II. patologickoanatomický ústav 1. LF UK a Katedra patologické anatomie IPVZ, Praha.
Cesk Patol. 1998 Jan;34(1):17-9.
We report a light microscopic and ultrastructural appearance, and immunohistochemical profile of two benign tumours of soft tissue recently designated as desmoplastic fibroblastoma (collagenous fibroma). The tumours were located in the foot and well demarcated. Microscopically, they were composed of stellate--or spindle--shaped cells embedded in a hypovascular fibrous of fibromyxoid stroma. Immunohistochemical examination showed that tumours were diffusely positive for vimentin and focaly positive for smooth muscle actin and muscle specific actin. Ultrastructurally, the neoplastic cells had features of fibroblasts and myofibroblasts.
我们报告了最近被命名为促纤维增生性纤维母细胞瘤(胶原纤维瘤)的两种软组织良性肿瘤的光镜和超微结构表现以及免疫组化特征。肿瘤位于足部,边界清晰。显微镜下,它们由嵌入血管较少的纤维黏液样基质中的星状或梭形细胞组成。免疫组化检查显示,肿瘤波形蛋白弥漫性阳性,平滑肌肌动蛋白和肌特异性肌动蛋白局灶性阳性。超微结构上,肿瘤细胞具有成纤维细胞和肌成纤维细胞的特征。