Enyedi L B, Loewenstein A, de Juan E
Wilmer Eye Institute, Baltimore, MD 21287-9227, USA.
Graefes Arch Clin Exp Ophthalmol. 1998 Apr;236(4):301-4. doi: 10.1007/s004170050082.
The duration of an intraocular gas bubble used in vitreoretinal surgery is an important determinant of the safety and effectiveness of intraocular gas use. Considerable variability impedes the clinical determination of this parameter. The aim of the study was to study experimentally the relationship between intraocular pressure (i.o.p.) and the absorption of an intravitreal air bubble.
We compared the rate of absorption of an intravitreal air bubble in rabbit eyes that had been treated with cyclocryotherapy (n = 17) to the absorption of air bubbles in untreated fellow eyes (n = 17).
Intravitreal air bubble persisted longer in the cyclocryotherapy-treated rabbit eye (mean +/- SD 78 +/- 16 h) than in the control fellow eyes (43 +/- 15 h). This difference was statistically significant (P < 0.001). The length of time an air bubble persisted could be predicted from the IOP.
The reason for the increased length of time an air bubble remained in cyclocryotherapy-treated eyes is probably the result of several factors, including primarily reduced aqueous flow and reduced IOP. Our results show that the duration of air injected into the vitreous cavity correlated to IOP. In addition to other known factors, the IOP should be considered in predicting intravitreal gas persistence.
玻璃体视网膜手术中眼内气泡的持续时间是眼内使用气体安全性和有效性的重要决定因素。较大的变异性阻碍了该参数的临床确定。本研究的目的是通过实验研究眼内压（IOP）与玻璃体内气泡吸收之间的关系。
我们比较了接受睫状体冷凝术治疗的兔眼（n = 17）中玻璃体内气泡的吸收速率与未治疗的对侧眼（n = 17）中气泡的吸收速率。
玻璃体内气泡在接受睫状体冷凝术治疗的兔眼中持续的时间（平均±标准差 78 ± 16 小时）比对照对侧眼（43 ± 15 小时）更长。这种差异具有统计学意义（P < 0.001）。气泡持续的时间可以根据眼压预测。
气泡在接受睫状体冷凝术治疗的眼中停留时间延长的原因可能是多种因素的结果，主要包括房水流动减少和眼压降低。我们的结果表明，注入玻璃体腔的气体持续时间与眼压相关。除了其他已知因素外，在预测玻璃体内气体持续时间时应考虑眼压。
