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Can clinically relevant histamine release be accurately diagnosed in anaesthetised patients without plasma histamine measurements? Randomised study with nested sampling aimed to change paradigms.

作者信息

Duda D, Lorenz W, Dick W, Celik I, Black A, Healy M J, Black J W

机构信息

Clinic of Anaesthesiology, Johannes Gutenberg University, Mainz Germany.

出版信息

Inflamm Res. 1998;47 Suppl 1:S73-4. doi: 10.1007/s000110050281.

DOI:10.1007/s000110050281
PMID:9561423
Abstract
摘要

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Can clinically relevant histamine release be accurately diagnosed in anaesthetised patients without plasma histamine measurements? Randomised study with nested sampling aimed to change paradigms.在不进行血浆组胺测量的情况下，能否准确诊断麻醉患者临床上相关的组胺释放？旨在改变范式的嵌套抽样随机研究。
Inflamm Res. 1998;47 Suppl 1:S73-4. doi: 10.1007/s000110050281.
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H1 and H2 blockade: a prophylactic principle in anaesthesia and surgery against histamine-release responses of any degree of severity: Part II.
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Models with clinically-relevant and life-threatening histamine-related cardiovascular disturbances: evaluation of the clinical effectiveness of H1/H2-histamine receptor antagonists in perioperative histamine release.具有临床相关性和危及生命的组胺相关心血管紊乱的模型：围手术期组胺释放中H1/H2组胺受体拮抗剂临床疗效的评估。
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