Pagano L, Pagliari G, Basso A, Marra R, Sica S, Frigieri L, Morace G, Ardito F, Leone G
Istituto di Semeiotica Medica, Università Cattolica del Sacro Cuore, Rome, Italy.
Ann Med. 1997 Dec;29(6):535-40. doi: 10.3109/07853899709007478.
In the aetiological diagnosis of pulmonary infections in patients affected by haematological malignancies we evaluated the utility of bronchoalveolar lavage (BAL). One hundred and twenty-seven BAL were performed in 119 patients. In our series, we identified the agent of pneumonia in 53.5% of episodes with the best results in aspergillosis, very common in these patients. The previous empirical anti-infective treatment was modified in 14 episodes (11%). The procedure was generally well tolerated and only one patient bled. We maintain that BAL is a useful diagnostic tool for detecting the agents of pulmonary infections in patients with haematological malignancies, especially when the routine microbiological procedures fail, and it also represents a good alternative to more invasive procedures.
在血液系统恶性肿瘤患者肺部感染的病因诊断中，我们评估了支气管肺泡灌洗（BAL）的效用。对119例患者进行了127次BAL。在我们的系列研究中，我们在53.5%的病例中确定了肺炎病原体，在曲霉病中取得了最佳结果，曲霉病在这些患者中非常常见。14例（11%）病例中先前的经验性抗感染治疗得到了调整。该操作总体耐受性良好，只有1例患者出血。我们认为，BAL是检测血液系统恶性肿瘤患者肺部感染病原体的有用诊断工具，尤其是在常规微生物学检查失败时，并且它也是更具侵入性检查的良好替代方法。
