Cojocaru M
N. Gh. Lupu Clinical Hospital, Department of Clinical Immunology, Bucharest, Romania.
Rom J Intern Med. 1997 Jan-Dec;35(1-4):77-82.
Serum total sialic acid and C-reactive protein (CRP) were studied in 68 patients with silicosis divided into 3 groups according to the evolutive stage of disease. The results were compared with the data obtained in a control group of 35 healthy subjects. The changes in serum total sialic acid levels were in parallel with those of CRP in silicosis. Patients in stage III had the highest mean values of serum total sialic acid (p < 0.01) and of CRP (p < 0.001). Linear regression analysis revealed a close positive correlation between serum total sialic acid and CRP levels in silicosis (r = 0.86, p < 0.01).
对68例矽肺患者进行了血清总唾液酸和C反应蛋白（CRP）的研究，这些患者根据疾病进展阶段分为3组。将结果与35名健康受试者的对照组数据进行比较。矽肺患者血清总唾液酸水平的变化与CRP的变化平行。Ⅲ期患者血清总唾液酸的平均值最高（p<0.01），CRP的平均值最高（p<0.001）。线性回归分析显示，矽肺患者血清总唾液酸与CRP水平之间存在密切的正相关（r=0.86，p<0.01）。
