冠状动脉支架置入术后早期出现的酷似败血症的噻氯匹定诱导的中性粒细胞减少症。
Ticlopidine-induced neutropenia mimicking sepsis early after intracoronary stent placement.
作者信息
Ochoa A B, Wolfe M, Lewis P, Lenihan D J
机构信息
Wright-Patterson Medical Center, Department of Internal Medicine, Wright-Patterson Air Force Base, OH 45433, USA.
出版信息
Clin Cardiol. 1998 Apr;21(4):304-7. doi: 10.1002/clc.4960210417.
Abstract
We report a case of ticlopidine-induced profound neutropenia early in the course of therapy, which was manifest as a febrile systemic illness mimicking sepsis. This clinical presentation was potentially indicative of a contaminated intracoronary stent. The patient's signs and symptoms of illness promptly resolved with removal of ticlopidine, and no infection was documented. Review of indications for ticlopidine use, potential adverse effects, and monitoring recommendations are discussed.
摘要
我们报告一例在治疗早期由噻氯匹定引起的严重中性粒细胞减少症，表现为类似败血症的发热性全身疾病。这种临床表现可能提示冠状动脉内支架受到污染。停用噻氯匹定后，患者的疾病体征和症状迅速缓解，且未记录到感染情况。本文讨论了噻氯匹定的使用指征、潜在不良反应及监测建议。
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