Shinhar D, Finaly R, Niska A, Mares A J
Department of Paediatric Surgery, Soroka Medical Centre, Faculty of Health Sciences, Ben-Gurion University, Beer-Sheba, Israel.
Pediatr Surg Int. 1998 Mar;13(2-3):84-7. doi: 10.1007/s003830050254.
Collagen-coated vicryl mesh (CCVM) was used experimentally to patch partial and total segmental defects in the canine cervical esophagus. The esophageal healing process over a 6-month period with successful incorporation of the CCVM and esophageal wall regeneration are described. Twenty-two (91.7%) of 24 dogs survived the procedure without any evidence of esophageal stricture or dysphagia. CCVM has proved to be a suitable material for substitution of esophageal tissue in the canine model. Its clinical use in congenital and acquired esophageal lesions should be considered only pending further experimental laboratory work.
胶原蛋白涂层的聚丙交酯乙交酯网(CCVM)被用于犬类颈段食管部分和全节段缺损的实验性修补。描述了6个月期间食管愈合过程,CCVM成功整合以及食管壁再生情况。24只犬中有22只(91.7%)手术存活,无食管狭窄或吞咽困难迹象。CCVM已被证明是犬类模型中替代食管组织的合适材料。仅在进一步的实验研究完成后,才应考虑其在先天性和后天性食管病变中的临床应用。