el-Shourbagy M, Diab K M, Abdalla M Y, el-Salam M A, Mohasb S H
Obstetrics and Gynaecology Department, Ain Shams Faculty of Medicine, Cairo, Egypt.
J Obstet Gynaecol Res. 1998 Feb;24(1):21-5. doi: 10.1111/j.1447-0756.1998.tb00047.x.
To evaluate the ability of leukocyte esterase dipstick test (LET) performed in cervical mucus to predict direct immunofluorescent (DIF)-verified Chlamydia trachomatis (Ct) cervical infection.
Eighty women with inflammatory cervico-vaginal smear were submitted to both an endocervical smear, to verify Ct cervicitis by DIF technique; and a cervical mucus sample to perform LET. Results of LET and DIF were matched.
Among 30 Chlamydial positive subjects, cervical mucus esterase test was positive in 28 (93.3%); while among 50 Chlamydial negative controls, esterase test was negative in 43 subject (86%). The sensitivity, specificity, positive and negative predictive values for LET were 93.3%, 86%, 80% and 95% respectively.
Cervical mucus LET is a simple, cost effective screening test, with promising accuracy, for Ct cervical infection among women with inflammatory cervico-vaginal smears.
评估在宫颈黏液中进行白细胞酯酶试纸检测（LET）以预测经直接免疫荧光（DIF）验证的沙眼衣原体（Ct）宫颈感染的能力。
80名宫颈阴道涂片有炎症的女性接受了宫颈管涂片检查，通过DIF技术验证是否患有Ct宫颈炎；同时采集宫颈黏液样本进行LET检测。将LET和DIF的结果进行比对。
在30名衣原体阳性受试者中，宫颈黏液酯酶检测阳性的有28名（93.3%）；而在50名衣原体阴性对照者中，酯酶检测阴性的有43名受试者（86%）。LET的敏感性、特异性、阳性预测值和阴性预测值分别为93.3%、86%、80%和95%。
对于宫颈阴道涂片有炎症的女性，宫颈黏液LET是一种简单、经济有效的筛查试验，对Ct宫颈感染具有较高的准确性。
