Chacko M R, Kozinetz C A, Hill R, Collins K, Dunne M, Hergenroeder A C
Department of Pediatrics and Pathology, Baylor College of Medicine, Houston, Texas, USA.
J Pediatr Adolesc Gynecol. 1996 Nov;9(4):185-9. doi: 10.1016/s1083-3188(96)70028-1.
To assess the ability of vaginal and cervical leukocyte esterase (LE) dipstick to detect vaginitis and cervicitis.
A prospective, cross-sectional study to assess the ability of the LE dipstick of vaginal secretions to detect trichomonads, candida, and bacterial vaginosis and the LE dipstick of vaginal and cervical secretions to detect gonococcal and chlamydia infection and polymorphonuclear cells (PMNs).
An inner-city shelter facility clinic.
183 sexually active, nonmenstruating females aged 13-21 years (Mean = 17.7, SD = 1.98 years): 47% black, 40% white, and 11% Hispanic.
Sensitivity (SN), specificity (SP), positive and negative predictive values (PVP, PVN), with 95% confidence intervals, of vaginal and cervical LE dipstick > or = trace in detecting vaginal and cervical infections.
A positive vaginal LE had a moderately high SN and PVN but poor SP and PVP in detecting trichomonas and candida vaginitis and bacterial vaginosis. A positive vaginal and cervical LE had a high SN and PVN but poor SP and PVP in detecting gonorrhea and chlamydia infection. A positive cervical LE had a moderate SN and low SP in detecting PMNs on Gram stain.
The LE dipstick of vaginal and cervical secretions was only a moderately good screening test for vaginal infection but a good screening test for cervical infection.
评估阴道和宫颈白细胞酯酶（LE）试纸检测阴道炎和宫颈炎的能力。
一项前瞻性横断面研究，以评估阴道分泌物LE试纸检测滴虫、念珠菌和细菌性阴道病的能力，以及阴道和宫颈分泌物LE试纸检测淋病和衣原体感染及多形核白细胞（PMN）的能力。
市中心收容所设施诊所。
183名年龄在13 - 21岁（平均 = 17.7岁，标准差 = 1.98岁）的性活跃、非经期女性：47%为黑人，40%为白人，11%为西班牙裔。
阴道和宫颈LE试纸检测阴道和宫颈感染时，≥微量结果的敏感度（SN）、特异度（SP）、阳性和阴性预测值（PVP、PVN）及其95%置信区间。
阴道LE试纸阳性在检测滴虫性、念珠菌性阴道炎和细菌性阴道病时，SN和PVN中等偏高，但SP和PVP较差。阴道和宫颈LE试纸阳性在检测淋病和衣原体感染时，SN和PVN较高，但SP和PVP较差。宫颈LE试纸阳性在革兰染色检测PMN时，SN中等，SP较低。
阴道和宫颈分泌物LE试纸对阴道感染只是一种中等程度的良好筛查试验，但对宫颈感染是一种良好的筛查试验。
