Barrington K J, Byrne P J
University of California, San Diego, Medical Center, 92103-8774, USA.
Am J Perinatol. 1998 Apr;15(4):213-6. doi: 10.1055/s-2007-993928.
The incidence of complications was recorded for 269 consecutive neonatal endotracheal intubations after instituting a routine policy of premedication. Two hundred and fifty-three of the intubations were premedicated with a combination of atropine, fentanyl and succinylcholine, 194 were without incident, 28 required two attempts, 22 required more than two attempts, and 9 required a second attempt with a smaller endotracheal tube. All infants were successfully intubated. We conclude that a policy of routine neonatal premedication for intubation is safe, feasible, and humane.
在制定了常规的术前用药方案后,对连续269例新生儿气管插管的并发症发生率进行了记录。其中253例插管术前使用了阿托品、芬太尼和琥珀酰胆碱的联合用药,194例插管过程顺利,28例需要两次尝试,22例需要两次以上尝试,9例需要更换较小的气管导管进行第二次尝试。所有婴儿均成功插管。我们得出结论,常规新生儿插管术前用药方案是安全、可行且人道的。