Tanaka N, Nagai I, Hiratsuka H, Kohama G
Department of Oral Surgery, Sapporo Medical University School of Medicine, Hokkaido, Japan.
Int J Oral Maxillofac Surg. 1998 Apr;27(2):111-4. doi: 10.1016/s0901-5027(98)80306-8.
Three patients with oral malignant melanoma, who survived for at least ten years after initial examination, are presented. The depth of tumor invasion was 5 mm or less in all patients. The first patient received surgery and postoperative immunotherapy and she had no recurrence more than 18 years after treatment. The second patient underwent surgery but had local recurrence after 11 years. He underwent resection and postoperative chemotherapy and was still alive more than 14 years after initial examination. The third patient received radiotherapy and had metastasis nine months after treatment. Resection and radiotherapy were performed and the patient was alive more than 14 years after first presentation.
本文报告了三例口腔恶性黑色素瘤患者，他们在初次检查后存活至少十年。所有患者的肿瘤浸润深度均为5毫米或更小。首例患者接受了手术及术后免疫治疗，治疗后18年以上无复发。第二例患者接受了手术，但11年后出现局部复发。他接受了切除术及术后化疗，初次检查后14年以上仍存活。第三例患者接受了放疗，治疗后九个月出现转移。进行了切除术及放疗，该患者首次就诊后14年以上仍存活。
