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Characterization of the region downstream of the pilus biogenesis gene pilC1 in Neisseria gonorrhoeae.

作者信息

Källström H, Jonsson A B

机构信息

Microbiology and Tumorbiology Center, Karolinska Institute, Box 280, 171 77 Stockholm, Sweden.

出版信息

Biochim Biophys Acta. 1998 Apr 29;1397(2):137-40. doi: 10.1016/s0167-4781(98)00007-4.

Abstract

The nucleotide sequence of a 3 kb region downstream of pilC1 in Neisseria gonorrhoeae MS11 was analyzed. This region contains two open reading frames, ORF1 and ORF2, and several repetitive DNA elements. ORF1 encodes an outer membrane protein that shows homology to orf98 of Pediococcus acidilactici. PCR with primers specific for ORF1 revealed that the gene is present in all gonococcal strains tested. The other open reading frame, ORF2, is highly homologous to the putative integral membrane protein HI1680 of Haemophilus influenzae.

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