利培酮治疗寄生虫妄想症。
Risperidone in the treatment of delusions of infestation.
作者信息
De León O A, Furmaga K M, Canterbury A L, Bailey L G
机构信息
Department of Psychiatry, University of Illinois at Chicago 60612, USA.
出版信息
Int J Psychiatry Med. 1997;27(4):403-9. doi: 10.2190/JJY8-P3YW-MN9Y-WBTX.
OBJECTIVE
The aim of this study is to describe the efficacy and safety of risperidone, in the treatment of delusions of infestation.
METHOD
The authors present a three-case series in which risperidone was used to treat delusions of infestation.
RESULTS
All three patients responded to risperidone and experienced no extrapyramidal side effects. Two of our patients had failed treatment with haloperidol and another had failed treatment with pimozide.
CONCLUSION
Risperidone was an effective and safe treatment in three cases of delusions of infestation. It is possible that 5-HT2 antagonism is essential for therapeutic benefit in this condition.
目的
本研究旨在描述利培酮治疗寄生虫妄想症的疗效和安全性。
方法
作者报告了一个三例系列病例，其中使用利培酮治疗寄生虫妄想症。
结果
所有三名患者对利培酮均有反应，且未出现锥体外系副作用。我们的两名患者使用氟哌啶醇治疗失败，另一名患者使用匹莫齐特治疗失败。
结论
利培酮对三例寄生虫妄想症患者是一种有效且安全的治疗方法。在这种情况下，5-羟色胺2（5-HT2）拮抗作用可能对治疗益处至关重要。
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