Herrmann N, Rivard M F, Flynn M, Ward C, Rabheru K, Campbell B
Sunnybrook Health Science Centre, University of Toronto, Royal Ottawa Hospital, University of Ottawa, Canada.
J Neuropsychiatry Clin Neurosci. 1998 Spring;10(2):220-3. doi: 10.1176/jnp.10.2.220.
The authors describe a series of 22 patients with dementia and behavioral disturbances, including agitation, aggression, delusions, and hallucinations, who were treated with risperidone. Risperidone, in low doses, was well tolerated; 50% of patients experienced significant improvement, although 50% experienced some extrapyramidal symptoms.
作者描述了一系列22名患有痴呆和行为障碍(包括激越、攻击行为、妄想和幻觉)的患者,他们接受了利培酮治疗。低剂量的利培酮耐受性良好;50%的患者有显著改善,尽管50%的患者出现了一些锥体外系症状。