Kleiner H, Stavric V l, Brouet-Yager M, Schwers H, Graff G L
J Gynecol Obstet Biol Reprod (Paris). 1976 Jan-Feb;5(1):25-37.
Plasma cystinylaminopeptidase (CAP) activity and 24 h urinary excretion of oestrogens were measured simultaneously in 102 pathological pregnancies. The correlation between the two chemical assays is weak (p = 0,13, to 0,47). Plasma CAP levels were significantly (p less than 0,01) lowered in cases of fetal death; but urinary oestrogen assays were within the normal limits (p greater than 0,1) in this group. Each assay suggested an equal number of correct or incorrect prognoses. Their association resulted in 9 correct prognoses in 12 pregnancies with unfavourable outcome, but led to 12 unduly bad prognoses in a group of 40 normal births. The association of the two assays allows a more adequate diagnosis of high-risk pregnancies, but has the disadvantage of offering an unduly bad prognosis in a greater number of normal cases.
在102例病理妊娠中，同时测定了血浆胱氨酰氨基肽酶（CAP）活性和雌激素的24小时尿排泄量。两种化学检测方法之间的相关性较弱（p = 0.13至0.47）。胎儿死亡病例的血浆CAP水平显著降低（p < 0.01）；但该组的尿雌激素检测结果在正常范围内（p > 0.1）。每种检测方法提示的正确或错误预后数量相等。它们的联合应用在12例预后不良的妊娠中得出了9个正确的预后，但在40例正常分娩的一组病例中导致了12个过度悲观的预后。两种检测方法的联合应用有助于更充分地诊断高危妊娠，但缺点是在更多正常病例中给出过度悲观的预后。
