Kyank H R
Zentralbl Gynakol. 1983;105(10):635-41.
The purpose of this study was to check the value of the determinations of human placental lactogen (HPL), urinary total estrogens and oxytocinase in 40 patients with fetal growth retardation among 253 single pregnancies using 3 methods of interpretation. The false-positive (abnormal) error of HPL was 40.4%. The sensitivity of urinary total estrogens was 22,5%, and of oxytocinase 30,8%. Therefore the intrauterine growth retardation can be predicted only in about a quarter of cases showing low levels or atypical profiles of these both biochemical determinations. The results suggest that the practical value is limited for all three determinations.
本研究的目的是采用三种解读方法,检查253例单胎妊娠中40例胎儿生长受限患者的人胎盘催乳素(HPL)、尿总雌激素和催产素酶测定值。HPL的假阳性(异常)误差为40.4%。尿总雌激素的敏感性为22.5%,催产素酶的敏感性为30.8%。因此,只有约四分之一的病例在这两种生化测定水平较低或呈非典型特征时,才能预测宫内生长受限。结果表明,这三种测定的实际价值有限。