Legrand D, Isaac J P, Philippe E, Dreyfus J
J Gynecol Obstet Biol Reprod (Paris). 1976 Apr-May;5(3):407-26.
The authors re-emphasize that the sure diagnosis of carcinoma of the cervix depends on histology; having considered a series of 15,000 smears in an article on cytological screening for carcinoma of the cervix. They show that the main prop of this histological examination should definitely be conisation. They furthermore prepare an inventory of the different possible methods of treatment of intra-epithelial carcinoma, stating for each method the advantages and disadvantages of the method. Their attitude to treatment is conservative, and they believe that conisation in every case is sufficient when complete removal of the in situ lesion is carried out whatever the age of the patient is. They state the limits of this method and define clearly the contra-indications for such a scheme of treatment, which can only be carried out routinely with the absolutely necessary cooperation of a cytology laboratory and faultless histology.
作者再次强调，子宫颈癌的确切诊断取决于组织学；在一篇关于子宫颈癌细胞学筛查的文章中，他们研究了一系列15000份涂片。他们表明，这种组织学检查的主要支柱肯定是锥形切除术。此外，他们还列出了上皮内癌不同可能治疗方法的清单，并针对每种方法阐述了其优缺点。他们对治疗的态度是保守的，并且认为无论患者年龄多大，只要能完全切除原位病变，在每种情况下进行锥形切除术就足够了。他们说明了这种方法的局限性，并明确界定了这种治疗方案的禁忌症，只有在细胞学实验室的绝对必要配合以及完美的组织学检查的情况下，才能常规实施这种治疗方案。
