Barrasso R, Ionesco M, Quinzat D, de Brux J
Rev Fr Gynecol Obstet. 1985 Jan;80(1):1-5.
A series of 111 cervical conization specimens from patients with carcinoma in situ (CIS) have been examined by the authors in order to point out the real incidence of condylomatous lesions and their different aspects. The histological criteria of condyloma and cervical intra-epithelial neoplasia (dysplasia and CIS) are recalled, and relationships between them are discussed. Koïlocytes have been observed in 77.5% of CIS examined. Different localisations of condylomatous aspects as regards dysplastic and neoplastic lesions are described and discussed. The histological pattern defined as CIN III with incomplete signs of condylomatous lesion, is significantly associated to flat condyloma (72.7% of cases). Morphological and biological border between condyloma and CIN seems to be not clean; therefore the authors stress on the careful screening, treatment and follow-up of this patients.
作者检查了111例原位癌（CIS）患者的宫颈锥切标本，以指出湿疣样病变的实际发生率及其不同表现。回顾了湿疣和宫颈上皮内瘤变（发育异常和原位癌）的组织学标准，并讨论了它们之间的关系。在所检查的原位癌中，77.5%观察到挖空细胞。描述并讨论了湿疣样表现相对于发育异常和肿瘤性病变的不同定位。定义为伴有不完全湿疣样病变征象的CIN III的组织学模式与扁平湿疣显著相关（72.7%的病例）。湿疣和CIN之间的形态学和生物学界限似乎并不清晰；因此，作者强调对这类患者进行仔细的筛查、治疗和随访。
