O'Neill D, O'Grady J, Variend S
Department of Histopathology, Sheffield Children's Hospital, United Kingdom.
Pediatr Pathol Lab Med. 1998 Jan-Feb;18(1):79-88.
We report a case of histiocytic necrotizing lymphadenitis without granulocytic infiltration (Kikuchi-Fujimoto disease), diagnosed at necropsy in a 19-month-old child dying unexpectedly after a febrile illness. This is the youngest case with this disease that has been thus far reported. It is one of only two reported cases in which the patient died during the acute phase of the illness. Histological findings not unlike those seen in the lymph nodes were present at extranodal sites; this is the first case in which this feature has been described. In keeping with many other reported cases, it was not possible to identify an underlying etiology that might explain the morphologic changes.
我们报告一例无粒细胞浸润的组织细胞性坏死性淋巴结炎（菊池-藤本病），该病例是在一名19个月大的儿童尸检时诊断出来的，该儿童在发热性疾病后意外死亡。这是迄今为止报道的患有该疾病的最年轻病例。这是仅有的两例报告病例之一，其中患者在疾病急性期死亡。在结外部位也出现了与淋巴结中所见相似的组织学表现；这是首次描述这一特征的病例。与许多其他报告病例一致，无法确定可能解释形态学变化的潜在病因。
