Shiraga F, Takasu I, Shiragami C
Department of Ophthalmology, Okayama University Medical School, Okayama, Japan.
Semin Ophthalmol. 1998 Mar;13(1):31-9. doi: 10.3109/08820539809066080.
Laser photocoagulation of the entire area of the neovascular lesion is the only proven treatment for subfoveal choroidal neovascularization secondary to age-related macular degeneration with a poor natural history. However, there are some limiting factors such as patient eligibility, a significant decline in visual acuity after treatment, and a very low possibility of a final vision of 20/100 or better. Although no large benefit of other treatment modalities, such as indocyanine green videoangiography-guided laser photocoagulation, surgical removal of neovascular membranes, and radiation therapy, has yet been proven, carefully selected patients may be suitable candidates for such treatments. This article reviews the status of treatment modalities for subfoveal choroidal neovascularization secondary to age-related macular degeneration, including laser photocoagulation of the entire area of the neovascular lesion, and discusses factors prognostic of visual outcome in these treatment options.
对于年龄相关性黄斑变性继发的黄斑下脉络膜新生血管且自然病程较差的情况，对新生血管病变的整个区域进行激光光凝是唯一经证实的治疗方法。然而，存在一些限制因素，如患者的入选标准、治疗后视力的显著下降以及最终视力达到20/100或更好的可能性非常低。尽管尚未证实其他治疗方式，如吲哚菁绿血管造影引导下的激光光凝、手术切除新生血管膜和放射治疗有很大益处，但经过精心挑选的患者可能适合这些治疗。本文综述了年龄相关性黄斑变性继发的黄斑下脉络膜新生血管的治疗方式现状，包括对新生血管病变整个区域的激光光凝，并讨论了这些治疗选择中视力预后的相关因素。
