Capuzzo M, Pavoni V, Paparella L, Facchini L, Poole D, Alvisi R, Gritti G
Istituto di Anestesiologia e Rianimazione, Università degli Studi, Ferrara.
Minerva Anestesiol. 1997 Oct;63(10):321-6.
To investigate the relationship between Therapeutic Intervention Scoring System (TISS), length of ICU stay and severity of illness.
Prospective study lasting 1 year.
Two 4-bed surgical-medical ICU.
All consecutively ICU admitted patients.
Every day TISS of each patient during the last 24 h was computed. Age, sex, type of admission, SAPS II and APACHE II, length of ICU stay and hospital outcome were recorded. Out of 446 admissions, 14 were excluded since the ICU stay was < 16 h. Severity of illness was considered in 405 of the remaining 432; total TISS of readmitted patients resulted from all ICU admissions during the same hospital stay.
Median TISS on day 1 was 24 (range 3-58, CI 95% 0.57) and median TISS +/- CI 95% during the first 10 ICU days ranged from 20 to 26. Spearman's correlation coefficient between TISS total and length of stay in ICU was 0.962. Total TISS increased with risk of hospital death predicted by both SAPS II and APACHE II. Total TISS of non surviving patients was significantly (p < 0.001) higher than that of the surviving up to probability of death of 20%.
Intensity of treatment is essentially steady and total TISS is well related to length of ICU stay. Total TISS increases with increasing risk of hospital death predicted by SAPS II and APACHE II, but it is high especially in non surviving patients with low probability of hospital mortality at the admission.
探讨治疗干预评分系统(TISS)、重症监护病房(ICU)住院时间与疾病严重程度之间的关系。
为期1年的前瞻性研究。
两个拥有4张床位的外科-内科ICU。
所有连续入住ICU的患者。
计算每位患者过去24小时内每天的TISS。记录年龄、性别、入院类型、简化急性生理学评分系统(SAPS II)和急性生理与慢性健康状况评分系统(APACHE II)、ICU住院时间和医院结局。在446例入院患者中,14例因ICU住院时间<16小时而被排除。对其余432例中的405例考虑疾病严重程度;再次入院患者的总TISS来自同一住院期间的所有ICU入院情况。
第1天的TISS中位数为24(范围3 - 58,95%置信区间0.57),ICU前10天的TISS中位数±95%置信区间为20至26。TISS总分与ICU住院时间之间的Spearman相关系数为0.962。SAPS II和APACHE II预测的医院死亡风险增加时,总TISS也增加。直至死亡概率为20%时,非存活患者的总TISS显著(p<0.001)高于存活患者。
治疗强度基本稳定,总TISS与ICU住院时间密切相关。SAPS II和APACHE II预测的医院死亡风险增加时,总TISS增加,但在入院时医院死亡率低的非存活患者中尤其高。