Egorov A P
Sud Med Ekspert. 1998 Jan-Feb;41(1):29-31.
Identification of phenothiazine 10-acyl derivatives by staining and spectrophotometry of their hydrolysis products 2-chlorophenothiazine, 2-trifluoromethylphenothiazine, and 2-carboxyaminophenothiazine appreciably improved the sensitivity and specificity of their detection. Staining on silufol plates detects at least 0.05 to 0.15 microgram per spot. The specific parameters of hydrolysis products absorption are notably superior to those of the native compounds and are (in chloroform, U1%1 cm): 1821 for 2-chlorophenothiazine, 1400 for 2-trifluoromethylphenothiazine, and 1656 for 2-carboxyaminophenothiazine.
通过对吩噻嗪10-酰基衍生物的水解产物2-氯吩噻嗪、2-三氟甲基吩噻嗪和2-羧基氨基吩噻嗪进行染色和分光光度测定来鉴定它们,显著提高了检测的灵敏度和特异性。在硅箔板上染色可检测到每斑点至少0.05至0.15微克。水解产物吸收的特定参数明显优于天然化合物,(在氯仿中,U1%1 cm):2-氯吩噻嗪为1821,2-三氟甲基吩噻嗪为1400,2-羧基氨基吩噻嗪为1656。