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[通过染色反应检测吩噻嗪的10-酰基衍生物及其水解产物的分光光度法]

[The detection of 10-acyl derivatives of phenothiazine by staining reactions and a spectrophotometric method for their hydrolysis products].

作者信息

Egorov A P

出版信息

Sud Med Ekspert. 1998 Jan-Feb;41(1):29-31.

PMID:9567678
Abstract

Identification of phenothiazine 10-acyl derivatives by staining and spectrophotometry of their hydrolysis products 2-chlorophenothiazine, 2-trifluoromethylphenothiazine, and 2-carboxyaminophenothiazine appreciably improved the sensitivity and specificity of their detection. Staining on silufol plates detects at least 0.05 to 0.15 microgram per spot. The specific parameters of hydrolysis products absorption are notably superior to those of the native compounds and are (in chloroform, U1%1 cm): 1821 for 2-chlorophenothiazine, 1400 for 2-trifluoromethylphenothiazine, and 1656 for 2-carboxyaminophenothiazine.

摘要

通过对吩噻嗪10-酰基衍生物的水解产物2-氯吩噻嗪、2-三氟甲基吩噻嗪和2-羧基氨基吩噻嗪进行染色和分光光度测定来鉴定它们,显著提高了检测的灵敏度和特异性。在硅箔板上染色可检测到每斑点至少0.05至0.15微克。水解产物吸收的特定参数明显优于天然化合物,(在氯仿中,U1%1 cm):2-氯吩噻嗪为1821,2-三氟甲基吩噻嗪为1400,2-羧基氨基吩噻嗪为1656。

相似文献

1
[The detection of 10-acyl derivatives of phenothiazine by staining reactions and a spectrophotometric method for their hydrolysis products].[通过染色反应检测吩噻嗪的10-酰基衍生物及其水解产物的分光光度法]
Sud Med Ekspert. 1998 Jan-Feb;41(1):29-31.
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[The separation of 10-alkyl derivatives and the hydrolysis products of 10-acyl derivatives of phenothiazine by an extraction method].[通过萃取法分离吩噻嗪的10-烷基衍生物和10-酰基衍生物的水解产物]
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New spectrophotometric method for the determination of phenothiazine derivatives.测定吩噻嗪衍生物的新分光光度法。
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[Spectrophotometric determination of some phenothiazine derivatives].[某些吩噻嗪衍生物的分光光度法测定]
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[Application of phenothiazine derivatives in analysis. 2].[吩噻嗪衍生物在分析中的应用。2]
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Determination of lipid bilayer/water partition coefficient of new phenothiazines using the second derivative of absorption spectra method.用吸收光谱二阶导数法测定新型吩噻嗪类化合物的脂双层/水分配系数
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[Identification and spectrophotometric quantitative determination of phenothiazine derivatives].[吩噻嗪衍生物的鉴定及分光光度法定量测定]
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