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聚维酮碘加新霉素用于浅表烧伤的持续研究

Povidone iodine plus neosporin in superficial burns--a continuing study.

作者信息

Sinha R, Agarwal R K, Agarwal M

机构信息

Department of Surgery, M.L.B. Medical College, Jhansi, India.

出版信息

Burns. 1997 Nov-Dec;23(7-8):626-8. doi: 10.1016/s0305-4179(97)00069-7.

Abstract

A total of 1053 patients with superficial burn injury were treated with povidone iodine plus neosporin (PVP + N) and the results after treatment were compared with those obtained after treating 1089 patients with silver sulphadiazine (SSD). Qualitative analysis showed Staphylococcus aureus and Pseudomonas spp. to be the most common infecting organisms. Quantitatively, fewer patients showed infection on the 7th and 18th day post-treatment in the PVP + N group (P < 0.01 and P < 0.001, respectively). Similarly, healing times were also better with PVP + N, with a maximum number of patients having healed within 15 days (P < 0.001). However, the mortality rates were not much different between the two groups.

摘要

共有1053例浅表烧伤患者接受了聚维酮碘加新霉素(PVP+N)治疗,并将治疗结果与1089例接受磺胺嘧啶银(SSD)治疗的患者的结果进行了比较。定性分析显示,金黄色葡萄球菌和假单胞菌属是最常见的感染病原体。从数量上看,PVP+N组在治疗后第7天和第18天出现感染的患者较少(分别为P<0.01和P<0.001)。同样,PVP+N组的愈合时间也更好,大多数患者在15天内愈合(P<0.001)。然而,两组的死亡率没有太大差异。

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