Broadie K
Department of Biology, University of Utah, Salt Lake City 84112-0840, USA.
Curr Opin Neurobiol. 1998 Feb;8(1):128-38. doi: 10.1016/s0959-4388(98)80016-0.
Genetic approaches at the neuromuscular synapse are leading investigation into the mechanisms of synaptogenesis. The marriage of classical (forward) and reverse genetic techniques allows the isolation and analysis of novel proteins involved in synaptic maturation and the functional in vivo characterization of previously identified synaptic proteins. Of particular interest are recent advances using mouse reverse genetics and Drosophila forward genetics.
