Bortolotti A, Parazzini F, Colli E, Landoni M
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.
Int J Androl. 1997 Dec;20(6):323-34. doi: 10.1046/j.1365-2605.1998.00081.x.
Erectile dysfunction (ED) affects millions of men throughout the world. The literature is ample, but an accurate estimate of its prevalence is still difficult since figures mainly refer to the USA, and are based mostly on small selected samples of people. Caution must anyway be used in comparing data from studies conducted in the past because of possible differences in the definition and classification of ED. Many factors are believed to contribute to the development and maintenance of ED. The influence of age and of several medical conditions (diabetes, vascular disease, and chronic diseases such as hepatic failure, renal failure and dialysis) is well defined. Also well documented is the role of some drug groups, whereas the role of other pharmacological agents is still controversial because of the frequent coexistence of other pathological conditions or concomitant exposure to other drugs. Less well defined and sometimes controversial is the role of risk factors mainly related to life-style such as cigarette smoking, alcoholism, total cholesterol levels and certain types of trauma. This paper reviews the main data on the epidemiology of ED and some related risk factors.
勃起功能障碍（ED）影响着全球数百万男性。相关文献丰富，但由于数据主要来自美国且大多基于小范围抽样人群，因此仍难以准确估计其患病率。鉴于ED的定义和分类可能存在差异，在比较过去研究的数据时仍需谨慎。许多因素被认为与ED的发生和持续存在有关。年龄以及几种疾病（糖尿病、血管疾病和诸如肝衰竭、肾衰竭及透析等慢性疾病）的影响已明确。某些药物组的作用也有充分记录，而其他一些药物的作用仍存在争议，因为常伴有其他病理状况或同时使用其他药物。与生活方式相关的危险因素，如吸烟、酗酒、总胆固醇水平及某些类型的创伤，其作用尚不明确，有时也存在争议。本文综述了ED流行病学的主要数据及一些相关危险因素。
