Kehayias J J, Zhuang H, Hughes V, Dowling L
US Department of Agriculture, Human Nutrition, Research Center on Aging at Tufts University, Boston, MA 02111, USA.
Appl Radiat Isot. 1998 May-Jun;49(5-6):723-5. doi: 10.1016/s0969-8043(97)00095-x.
Based on the observation that the carbon-to-oxygen ratio (C/O) in tissue is a measure of fat content, we developed a model which correlates C/O to percent body fat. Carbon and oxygen mass and their ratio are measured in vivo by fast neutron inelastic scattering, using a miniature D-T neutron generator, at a radiation exposure of less than 0.06 mSv. We tested the validity of this model against hydrodensitometry with 19 healthy adult volunteers. The method was found to be accurate and insensitive to assumptions about the composition of lean tissue and, therefore, appropriate for studying the elderly and patients with catabolic conditions.
基于组织中的碳氧比（C/O）是脂肪含量的一种度量这一观察结果，我们开发了一个将C/O与体脂百分比相关联的模型。使用微型D-T中子发生器，通过快中子非弹性散射在体内测量碳和氧的质量及其比率，辐射暴露量小于0.06 mSv。我们用19名健康成年志愿者对照水下密度测量法测试了该模型的有效性。结果发现该方法准确，并且对瘦组织成分的假设不敏感，因此适用于研究老年人和患有分解代谢状况的患者。
