Kehayias J J, Smith D E, Roubenoff R, Savicki M, Zhuang H
United States Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA.
Appl Radiat Isot. 1998 May-Jun;49(5-6):737-8. doi: 10.1016/s0969-8043(97)00098-5.
Elemental Partition Analysis (EPA) is a new approach to body composition. A major element of the body is measured and then, by means of other measurements, is partitioned to the contributing body compartments. We developed a model for measuring total body muscle by applying the EPA method to total body phosphorus (TBP). We measure TBP (head excluded) by in vivo fast neutron activation analysis using the reaction 31P(n, alpha)28 Al. The main contributors to TBP are the bone and skeletal muscle. Adipose tissue and the liver contribute less than 3%. We use dual-energy X-ray absorptiometry (DXA) to evaluate the contribution of bone to TBP. Corrections are applied for the small contributions of the liver and adiopose tissue to TBP to derive muscle phosphorous. The technique requires high precision measurements for both TBP (+/- 2%) and DXA (+/- 1%). The total body radiation exposure for measuring human subjects is 0.60 mSv. We observed that nitrogen can also be measured by fast neutron activation analysis through the (n,2n) reaction, simultaneously with TBP.
元素分配分析（EPA）是一种用于身体成分分析的新方法。测量身体中的一种主要元素，然后通过其他测量手段，将其分配到各个身体组成部分。我们通过将EPA方法应用于全身磷（TBP），开发了一种测量全身肌肉的模型。我们使用反应31P(n, α)28Al，通过体内快中子活化分析来测量TBP（不包括头部）。TBP的主要贡献者是骨骼和骨骼肌。脂肪组织和肝脏的贡献不到3%。我们使用双能X射线吸收法（DXA）来评估骨骼对TBP的贡献。对肝脏和脂肪组织对TBP的小贡献进行校正，以得出肌肉磷含量。该技术要求对TBP（±2%）和DXA（±1%）进行高精度测量。测量人体受试者时的全身辐射暴露量为0.60毫希沃特。我们观察到，氮也可以通过快中子活化分析，通过(n,2n)反应与TBP同时测量。
