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被孢霉属和小克银汉霉属物种中前列腺素及其前体的含量。

The content of prostaglandins and their precursors in Mortierella and Cunninghamella species.

作者信息

Lamacka M, Sajbidor J

机构信息

Department of Biochemical Technology, Chemical Faculty, Slovak Technical University, Bratislava, Slovak Republic.

出版信息

Lett Appl Microbiol. 1998 Mar;26(3):224-6. doi: 10.1046/j.1472-765x.1998.00324.x.

Abstract

Five strains of filamentous fungi belonging to the genera Mortierella and Cunninghamella were examined for the content of dihomo-gamma-linolenic, arachidonic, eicosapentaenoic acids and prostaglandins (type E2 and F2 alpha). Prostaglandins were detected using an ELISA method in mycelia of all tested strains (range 50-4800 ng g-1 of PGE2 and 6-30 ng g-1 of PGF2 alpha). Several micro-organisms also produced prostaglandins in the culture medium (2.2-137.6 micrograms 1-1 for PGE2 and 0.4-7.8 micrograms 1-1 for PGF2 alpha).

摘要

对五株属于被孢霉属和小克银汉霉属的丝状真菌进行了二高-γ-亚麻酸、花生四烯酸、二十碳五烯酸和前列腺素(E2型和F2α型)含量的检测。使用酶联免疫吸附测定法在所有受试菌株的菌丝体中检测到了前列腺素(PGE2含量范围为50 - 4800 ng g-1,PGF2α含量范围为6 - 30 ng g-1)。几种微生物在培养基中也产生了前列腺素(PGE2为2.2 - 137.6微克1-1,PGF2α为0.4 - 7.8微克1-1)。

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