Pileri S A, Roncador G, Ceccarelli C, Piccioli M, Sabattini E, Briskomatis A, Santini D, Leone O, Piccaluga P P, Leoncini L, Falini B
Second Service of Pathologic Anatomy/Unit of Haematopathology, Bologna University, S. Orsola Hospital, Italy.
Leuk Lymphoma. 1997 Dec;26 Suppl 1:69-75. doi: 10.3109/10428199709058602.
In a percentage of cases, conventional morphologic evaluation of bone-marrow needle biopsy (BMNB) in insufficient to achieve a firm diagnosis. Under these circumstances, immunohistochemistry plays a basic role, providing an easy and objective key for the interpretation of the pattern observed in most instances. Herein, the authors focus on the technical procedures, which allow extensive application of immunohistochemistry to the study of BMNB, as well as on the panels of antibodies needed for the identification of the most relevant conditions.
在一定比例的病例中，骨髓穿刺活检（BMNB）的传统形态学评估不足以做出明确诊断。在这种情况下，免疫组织化学发挥着重要作用，为大多数情况下观察到的模式解读提供了一个简便且客观的关键方法。在此，作者着重介绍了一些技术程序，这些程序可使免疫组织化学广泛应用于BMNB的研究，同时也介绍了用于识别最相关病症所需的抗体组合。
