Kitoh T, Nishimura S, Fukuda S, Hirabuki S, Kaganoi J, Tokunaga Y, Ohsumi K
Department of Pediatrics, Maizuru Municipal Hospital, Kyoto, Japan.
Am J Perinatol. 1998 Mar;15(3):165-71. doi: 10.1055/s-2007-993919.
Colorectal cancer during pregnancy is very rare. We report two additional cases of rectal carcinoma. A 34-year-old woman with an obstructive adenocarcinoma of the rectal region was diagnosed at labor. A 35-year-old woman with an adenocarcinoma of the rectal region was diagnosed at 32 weeks of gestation and underwent a cesarean section and rectal resection at 35 weeks of gestation. A retrospective review of the Japanese literature was performed to identify patients who appeared to have primary colorectal cancer during pregnancy. Thirty-six patients with colon cancer (75.0%), 10 (20.8%) with rectal cancer, and two (4.2%) of unknown sites have been reported in Japanese series. The average age of the mother was 32.2 years. The calculated incidence of colorectal cancer among Japanese pregnant women was one case per 502,316 live births during the years between 1986 through 1995. Although the majority of colorectal cancers diagnosed during pregnancy are rectal carcinomas, the patients in Japan were predominantly complicated by colon cancer. The fetal risk seems small, because there were no cases of colorectal cancer metastatic to the products of conception.
妊娠期结直肠癌非常罕见。我们报告另外两例直肠癌病例。一名34岁女性在分娩时被诊断为直肠区域梗阻性腺癌。一名35岁女性在妊娠32周时被诊断为直肠区域腺癌，并在妊娠35周时接受了剖宫产和直肠切除术。我们对日本文献进行了回顾，以确定妊娠期似乎患有原发性结直肠癌的患者。日本系列报道中，有36例结肠癌患者（75.0%），10例（20.8%）直肠癌患者，2例（4.2%）部位不明。母亲的平均年龄为32.2岁。1986年至1995年间，日本孕妇中结直肠癌的计算发病率为每502,316例活产中有1例。虽然妊娠期诊断出的大多数结直肠癌是直肠癌，但日本的患者主要并发结肠癌。胎儿风险似乎较小，因为没有结直肠癌转移至妊娠产物的病例。
