Dargie H J, Dollery C T, Daniel J
Department of Clinical Pharmacology, Royal Postgraduate Medical School, London.
Lancet. 1977 Sep 10;2(8037):515-8. doi: 10.1016/s0140-6736(77)90660-2.
Minoxidil in combination with propranolol and diuretics controlled the blood-pressure in a group of hypertensive patients who were resistant to treatment with large doses of standard drugs. The main problem was fluid retention but subjective side-effects were fewer than in a comparable group on other drugs.
米诺地尔与普萘洛尔及利尿剂联合使用,可控制一组对大剂量标准药物治疗有抵抗性的高血压患者的血压。主要问题是液体潴留,但与使用其他药物的对照组相比,主观副作用较少。