Woutersz T B
J Reprod Med. 1976 Jun;16(6):338-44.
Updated data are presented that span 43 cycles of use of norgestrel 0.030 mg as a lower-dose combination oral contraceptive. Active participation by 1,633 women in 20,312 treatment cycles has resulted in a use-effectiveness rate of 0.13 per 100 woman-years. Satisfactory cycle control, minimal menstrual irregularities and a low incidence of side effects produced high acceptability among users. No drug toxicity was demonstrated. The incidence of discontinuance for medical reasons was low.
本文呈现了炔诺孕酮0.030毫克作为低剂量复方口服避孕药43个使用周期的更新数据。1633名女性积极参与了20312个治疗周期，使用有效率为每100妇女年0.13。令人满意的周期控制、极少的月经不规律以及低副作用发生率使得使用者的接受度很高。未显示出药物毒性。因医学原因停药的发生率很低。
