Junginger T, Dutkowski P
Klinik und Poliklinik für Allgemein- und Abdominalchirurgie, Klinikum der Johannes-Gutenberg-Universität Mainz.
Langenbecks Arch Chir Suppl Kongressbd. 1997;114:146-51.
Tumor stage and tumor localization (suprabifurcal and infrabifurcal) are the two decisive criteria referred to in the surgical treatment of esophageal cancer. Complete tumor resection (R0 resection) is a prerequisite for curative efforts. The thoracic squamous cell tumors are adequately treated by an abdominothoracic resection with abdominal and mediastinal lymph node dissection. The transmediastinal approach does not meet the requirements of an oncological resection and is only indicated under special conditions. In contrast the distal adenocarcinomas (Barrett carcinoma) can be curatively resected by both surgical approaches, the transthoracic and the transmediastinal. Presently, an adjuvant therapy after R0 resection of esophageal cancer is not indicated outside of clinical studies. Neoadjuvant methods in case of a local advanced tumor are currently being clinically tested.
肿瘤分期和肿瘤定位(分叉上和分叉下)是食管癌外科治疗中提到的两个决定性标准。完整的肿瘤切除(R0切除)是进行治愈性治疗的前提条件。胸段鳞状细胞肿瘤通过胸腹联合切除并进行腹部和纵隔淋巴结清扫可得到充分治疗。经纵隔入路不符合肿瘤切除的要求,仅在特殊情况下适用。相比之下,远端腺癌(巴雷特癌)可通过经胸和经纵隔这两种手术入路进行根治性切除。目前,在临床研究之外,不建议在R0切除术后对食管癌进行辅助治疗。对于局部晚期肿瘤,新辅助治疗方法目前正在进行临床试验。