Kakhnovskiĭ I M, Marinin V F, Arkhipova S V, Sorokina L A
Ter Arkh. 1998;70(3):22-5.
Study of efficiency of inhalation glucocorticosteroid Aldecine.
A 4-week trial of 30 patients with bronchial asthma. Treatment results were evaluated by clinical symptoms, demand of inhalation sympathomimetics, external respiration, viscosity and elasticity of bronchial secretion, concentrations of hydrocortisone and thyroid hormones.
Aldecine produced a good clinical effect, improved external respiration, allowed to reduce doses of inhalation beta-adrenomimetics. No deterioration of either bronchial secretion rheology or inhibition of adrenal and thyroid function was seen. Candidiasis was clinically negligible.
Aldecine proved highly effective and tolerable in patients with bronchial asthma.
研究吸入性糖皮质激素阿尔德新的疗效。
对30例支气管哮喘患者进行为期4周的试验。通过临床症状、吸入拟交感神经药的需求、肺通气、支气管分泌物的黏稠度和弹性、氢化可的松及甲状腺激素浓度评估治疗效果。
阿尔德新产生了良好的临床效果,改善了肺通气,可减少吸入性β-肾上腺素能激动剂的剂量。未观察到支气管分泌流变学恶化或肾上腺及甲状腺功能受抑制。念珠菌病在临床上可忽略不计。
阿尔德新在支气管哮喘患者中证明是高效且耐受性良好的。