Nesterov Iu I, Ivanova I V, Gol'dberg G A
Klin Med (Mosk). 1998;76(3):41-3.
An antihypertensive action and tolerance of prestarium and lomir were studied in 31 and 33 hypertensive patients, respectively. They had hypertension stage I-II and took the drug for 12 months. Monotherapy with prestarium in a dose 8 mg/day and lomir (10 mg/day) given twice a day provides a complete hypotensive effect for a year in 56 and 62% of patients, respectively. Combinations prestarium + ariphon, lomir + anapriline or verapamil increased the above number to 100%. The occurrence of side effects of long-term lomir monotherapy was 4 times higher than due to prestarium therapy (39.4 versus 9.7%, respectively).
分别在31例和33例高血压患者中研究了普雷斯他明和洛米尔的降压作用及耐受性。这些患者处于I-II期高血压，服用药物12个月。每日8毫克剂量的普雷斯他明单药治疗以及每日两次服用洛米尔（10毫克/天）分别使56%和62%的患者在一年内获得完全降压效果。普雷斯他明+阿利芬、洛米尔+阿那普利或维拉帕米的联合用药使上述比例提高到100%。长期洛米尔单药治疗的副作用发生率比普雷斯他明治疗高4倍（分别为39.4%和9.7%）。
