Karczewicz D, Pielich G
Katedry i Kliniki Okulistyki z Zakładem Patofizjologii Narzadu Wzroku Pomorskiej AM w Szczecinie.
Klin Oczna. 1997;99(4):261-3.
The paper presents a case of a 44 years old man, K.Z., with an invasive carcinoma of cornea and conjunctiva of his left eye. The patient was hospitalized for the first time eight years ago due to a viral keratitis of this eye, afterwards for three times due to changes within his cornea and conjunctiva in form of a cauliflower-like whitepink small tumour at the conjunctiva-cornea border line. During his last hospitalization the change covered two thirds of the cornea and it was going over onto the bulbar conjunctiva. The fourfold cytological and histopathological assays of the change did not show carcinomatous cells, but only cells of multi-layer, flat epithelium with features of excessive cornification. It is only the last histopathological assay of the cut-off small tumour that showed that it was carcinoma planoepitheliale keratodes invasivum. The consultant radiologists recommended removing the eye bulb since high radiation doses, which would be necessary, would destroy the eye bulb and yield postradiation reactions. The histopathological assays of the enucleated eye bulb confirmed the diagnosis and showed the superficial infiltration of the conjuctiva border. The patient was subjected to the X-ray treatment over the conjunctival sac region.
本文介绍了一例44岁男性K.Z.，患有左眼角膜和结膜浸润性癌。该患者八年前因左眼病毒性角膜炎首次住院，此后又因角膜和结膜出现变化，即在结膜-角膜边界线处出现菜花状白色粉红色小肿瘤，而三次住院。在他最后一次住院期间，病变覆盖了角膜的三分之二，并蔓延至球结膜。对该病变进行的四次细胞学和组织病理学检测均未发现癌细胞，仅发现具有过度角化特征的多层扁平上皮细胞。只有对切除的小肿瘤进行的最后一次组织病理学检测显示为浸润性扁平上皮角膜癌。放射科会诊医生建议摘除眼球，因为所需的高辐射剂量会破坏眼球并产生放疗后反应。摘除眼球的组织病理学检测证实了诊断，并显示结膜边界有浅表浸润。患者接受了结膜囊区域的X射线治疗。
