Birdsall T C
Thorne Research, Inc., Dover, ID 83825, USA.
Altern Med Rev. 1998 Apr;3(2):128-36.
Taurine is a conditionally-essential amino acid which is not utilized in protein synthesis, but rather is found free or in simple peptides. Taurine has been shown to be essential in certain aspects of mammalian development, and in vitro studies in various species have demonstrated that low levels of taurine are associated with various pathological lesions, including cardiomyopathy, retinal degeneration, and growth retardation, especially if deficiency occurs during development. Metabolic actions of taurine include: bile acid conjugation, detoxification, membrane stabilization, osmoregulation, and modulation of cellular calcium levels. Clinically, taurine has been used with varying degrees of success in the treatment of a wide variety of conditions, including: cardiovascular diseases, hypercholesterolemia, epilepsy and other seizure disorders, macular degeneration, Alzheimer's disease, hepatic disorders, alcoholism, and cystic fibrosis.
牛磺酸是一种条件必需氨基酸，它不参与蛋白质合成，而是以游离形式或存在于简单肽中。研究表明，牛磺酸在哺乳动物发育的某些方面至关重要，对各种物种的体外研究表明，低水平的牛磺酸与各种病理损伤有关，包括心肌病、视网膜变性和生长发育迟缓，尤其是在发育过程中出现缺乏时。牛磺酸的代谢作用包括：胆汁酸结合、解毒、膜稳定、渗透压调节和细胞钙水平调节。临床上，牛磺酸在治疗多种疾病方面已取得不同程度的成功，这些疾病包括：心血管疾病、高胆固醇血症、癫痫和其他发作性疾病、黄斑变性、阿尔茨海默病、肝脏疾病、酒精中毒和囊性纤维化。
