Mukherji S K, Figueroa R E, Ginsberg L E, Zeifer B A, Marple B F, Alley J G, Cooper L L, Nemzek W R, Yousem D M, Jones K R, Kupferberg S B, Castillo M
Department of Radiology, University of North Carolina School of Medicine, Chapel Hill 27599-7510, USA.
Radiology. 1998 May;207(2):417-22. doi: 10.1148/radiology.207.2.9577490.
To determine the computed tomographic (CT) findings in patients with allergic fungal sinusitis.
The authors retrospectively reviewed CT scans and surgical and histopathologic reports in 45 patients (27 male, 18 female; age range, 8-68 years) with allergic fungal sinusitis from multiple institutions. The median age (25 years) and demographics of the patients were determined. Two head and neck radiologists together evaluated the CT scans for the presence of intrasinus high-attenuation areas, extent of sinus involvement, bone expansion and thinning, bone erosion, and extension of disease into the adjacent soft tissues.
Allergic fungal sinusitis was more common in male patients and in patients aged 20-30 years. All patients had increased intrasinus attenuation at non-contrast material-enhanced CT. Multiple sinus involvement occurred in 43 patients. Bilateral involvement was more common than unilateral disease. Forty-four patients had complete opacification of at least one of the involved sinuses; 43 of these patients had expansion of an involved sinus, 42 had remodeling and thinning of the bony sinus walls, and 41 had erosion of the sinus wall.
Allergic fungal sinusitis is a distinct clinical entity with nonspecific symptoms that may be initially suggested by the CT findings. These findings should alert the clinician to the possibility of allergic fungal sinusitis and prompt other diagnostic studies to establish the diagnosis and treatment plan.
确定变应性真菌性鼻窦炎患者的计算机断层扫描(CT)表现。
作者回顾性分析了来自多个机构的45例变应性真菌性鼻窦炎患者(男27例,女18例;年龄范围8 - 68岁)的CT扫描以及手术和组织病理学报告。确定了患者的中位年龄(25岁)和人口统计学特征。两位头颈放射科医生共同评估CT扫描,以确定鼻窦内高密度区的存在、鼻窦受累范围、骨质膨胀和变薄、骨质侵蚀以及疾病向邻近软组织的蔓延情况。
变应性真菌性鼻窦炎在男性患者和20 - 30岁患者中更为常见。所有患者在非增强CT上鼻窦内密度均增加。43例患者累及多个鼻窦。双侧受累比单侧病变更常见。44例患者至少有一个受累鼻窦完全闭塞;其中43例患者受累鼻窦有扩张,42例有鼻窦骨壁重塑和变薄,41例有鼻窦壁侵蚀。
变应性真菌性鼻窦炎是一种具有非特异性症状的独特临床实体,CT表现可能最初提示该病。这些表现应提醒临床医生注意变应性真菌性鼻窦炎的可能性,并促使进行其他诊断性检查以确立诊断和治疗方案。