Sakaguchi S, Miyajima Y, Tohara K
Chikushi Hospital, Fukuoka University.
Nihon Rinsho. 1998 Apr;56(4):947-50.
The findings of enhanced ultrasonography under the injection of microbubbles of carbon dioxide into a hepatic artery (CO2-US) were evaluated in the patients with hepatocellular carcinoma (HCC). They were as follows. Most nodules showed early (within 3 seconds) stronger enhancement compared to the surrounding hepatic parenchyma, remaining the enhancing effects more longer than the surround. A few nodule showed isoenhance or nonenhancement. However, metastatic cancer of the liver often showed the early enhancement only at the edge of tumor. In hepatic hemangioma, only the spotty enhancement in the tumor and or the later (later than 4 seconds) enhancement at the edge of tumor was showed. The hyperenhanced mass was detected more often in a larger HCC and revealed to be a relatively poorly differentiated HCC with the capsule formation.
对肝细胞癌（HCC）患者进行了肝动脉内注射二氧化碳微泡增强超声检查（CO2-US），结果如下。大多数结节与周围肝实质相比，在早期（3秒内）表现出更强的增强，增强效应持续时间比周围更长。少数结节表现为等增强或无增强。然而，肝转移癌通常仅在肿瘤边缘表现出早期增强。在肝血管瘤中，仅显示肿瘤内的斑点状增强和/或肿瘤边缘的延迟（4秒后）增强。较大的HCC中更常检测到高增强肿块，且显示为相对低分化的有包膜形成的HCC。
